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Designed for Process Development, Scale-Up
More Than a Manufacturer

PILOT FREEZE DRYER

Scale-Up Solution Provider
Engineered for pilot-scale freeze drying, SONYAN silicone oil heated freeze dryers provide precise shelf temperature control, stable vacuum performance, and reliable process reproducibility from laboratory development to pre-production manufacturing.
PILOT FREEZE DRYER
PRODUCT LINEUP

Pilot Freeze Dryers for Different Scale-Up Requirements

Designed for formulation optimization and pilot-scale freeze-drying studies.

Supports vial stoppering and pharmaceutical process development applications.

CATEGORY INTRODUCTION

Why Choose a Dedicated Pilot Freeze Dryer?

Unlike conventional laboratory freeze dryers, pilot systems are designed to simulate industrial production conditions, making them essential for formulation optimization, process validation, and production scale-up.
Silicone Oil Heated Shelves
Excellent shelf temperature uniformity for consistent sublimation performance.
Industrial Process Simulation
Replicates production freeze-drying conditions for accurate scale-up studies.
Supports Bulk & Vial Applications

Suitable for tray-loaded materials and vial stoppering processes.

Stable Vacuum & Condenser Coordination

Ensures efficient moisture capture and stable drying performance.

≤-80℃
Cold Trap Temperature
±1℃
Shelf Temperature Uniformity
Pilot Freeze Dryer Manufacturer
KEY TECHNICAL FEATURES

Engineered for Reliable Scale-Up and Process Consistency

Pilot freeze dryers are engineered not only as equipment, but as a process simulation platform, ensuring that laboratory formulations can be reliably transferred into industrial production conditions.
Shelf Temperature Range:
-55°C to +70°C

Wide temperature control range suitable for freezing, primary drying, and secondary drying processes.

Ultimate Vacuum: ≤ 1 Pa
High-vacuum environment supports efficient sublimation and low residual moisture content.
High-Capacity Ice Condenser Design
Ensures stable vapor capture during long cycles and high moisture loads.
Programmable Freeze-Drying Recipes
Stores up to 100 freeze-drying programs, with up to 36 process steps per recipe.

Unlocking Possibilities with a Pilot Freeze Dryer

Process Development Across Multiple Industries
Pharmaceutical & Biopharmaceutical Process Development

Pharmaceutical & Biopharmaceutical Process Development

Injectable formulations (small molecule drugs, antibiotics)
Ensure stable solid-state structure and improve long-term storage stability.
Biologics (antibodies, recombinant proteins, enzymes)
Preserve bioactivity and prevent denaturation during dehydration.
Vaccine freeze-drying process development
Improve thermal stability for long-term cold-chain reduction and storage flexibility.
Diagnostic reagents and in vitro test kits (IVD products)
Enable rapid reconstitution and stable shelf-life performance.
Cosmetics & Personal Care Product Development

Cosmetics & Personal Care Product Development

Cosmetic active ingredients (peptides, hyaluronic acid, collagen)

Preserve bioactivity and prevent degradation of heat- and oxidation-sensitive cosmetic compounds.

Freeze-dried facial masks and solid essence formulations

Enable stable structure formation and improve rehydration performance for end-use products.

High-performance skincare powders and functional actives

Improve stability, shelf life, and dosing accuracy of premium skincare ingredients.

Natural extracts and plant-based cosmetic ingredients

Maintain antioxidant activity and prevent loss of volatile components during drying.

Advanced Materials & Energy Storage Systems

Advanced Materials & Energy Storage Systems

Battery electrode materials and slurry systems

Preserve porous structure and improve electrochemical consistency.

Graphene, nano oxides, and advanced nanomaterials

Prevent agglomeration and maintain dispersion stability.

Aerogel and ultra-light porous materials

Achieve structure preservation during critical drying stages.

Functional energy materials and composite systems

Support development of high-performance energy storage materials.

Chemical & Fine Chemical Process Development

Chemical & Fine Chemical Process Development

Heat-sensitive chemical intermediates

Prevent thermal degradation during solvent removal and drying stages.

High-purity chemical compounds and specialty materials

Ensure structural integrity and purity retention during dehydration.

Catalysts and porous functional materials

Maintain surface area and prevent structural collapse during drying.

Solvent-free drying of functional chemical systems

Enable clean and residue-free material processing.

Food & Nutritional Product Development

Food & Nutritional Product Development

Freeze-dried coffee, tea, and instant beverages

Preserve aroma, flavor, and solubility through low-temperature vacuum dehydration.

Functional foods and dietary supplements

Maintain nutritional activity and improve product stability and shelf life.

Premium snack products (fruit, dairy, meat-based foods)

Enable high-quality texture retention and rehydration performance.

Pet food freeze-drying process development

Improve palatability and nutrient retention in premium pet nutrition products.

WHY SONYAN?

Pilot Freeze Dryer Solutions for Reliable Scale-Up

SONYAN pilot freeze dryer systems are engineered to bridge laboratory development and industrial production,
ensuring stable, reproducible, and scalable freeze-drying performance.

Scale-Up Focused Design

Lab-to-production transfer based on real product behavior in freeze drying.

Reduced Process Risk

Minimize formulation loss, structural collapse, and batch deviation during pilot validation.

Industrial Operating Reliability

Designed for continuous industrial freeze drying conditions, not laboratory environments.

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CE-2024
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R&D Freeze Dryer FAQ

Q: What is the difference between a pilot freeze dryer and a laboratory freeze dryer?
A laboratory freeze dryer is mainly used for small-scale R&D and sample testing, while a pilot freeze dryer simulates industrial production conditions with larger capacity, more stable process control, and better scalability.
Q: What factors affect freeze-drying time in a pilot freeze dryer?
Key factors include product composition, layer thickness, freezing method, primary drying pressure, and secondary drying temperature. Optimization of these parameters is critical for scale-up consistency.
Q: Can a pilot freeze dryer be used for GMP production?
Pilot freeze dryers can support GMP process development and validation batches when equipped with appropriate documentation, data logging, and compliance options, but final production typically requires validated industrial systems.
Q: What industries commonly use pilot freeze dryers?
Pilot freeze dryers are widely used in pharmaceuticals, biotechnology, food processing, chemical engineering, and advanced materials development for process scale-up and formulation optimization.
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Keep in touch with us

Whether you need a benchtop unit for sample prep or a pilot-scale R&D Freeze Dryer for clinical trials, our technical support team is ready to assist you.

Tel: +86-13161061539

E-mail:info@freezedryersales.com

Address:Room 706 Tower C, Changyin Building, No.88 Yongding Road, Haidian District, Beijing, China

Contact Us

Beijing Songyuan Huaxing Technology Development Co., Ltd. was founded in 2000, with its headquarters located in Beijing, China.

CONTACT US

+86-13161061539
 +86-13161061539
+86-10-58895377
  info@freezedryersales.com
  Room 706 Tower C, Changyin Building, No.88 Yongding Road, Haidian District, Beijing, China
 
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